Diet

Toasting to good health? Consider putting down your glass...

Alcohol consumption has been convincingly linked to an increased risk of several types of cancer, including breast, liver, lung, esophageal, colorectal, pancreatic, prostate, and head and neck cancers. It also may increase stomach cancer risk[1]. When the body metabolizes alcohol, it produces acetaldehyde, a mutagen[2] that can damage DNA and proteins. Free radicals produced during alcohol metabolism can do further damage to cells. Alcohol can also influence hormone levels and impair nutrient absorption. 

While recent studies indicate that any alcohol consumption increases your overall risk of cancer, the relationship between alcohol and cancer risk is dose-responsive[3]. This means that the more alcohol consumed, the higher the risk. The risk increase is sharp between moderate drinking (defined as 2 or fewer drinks daily for men, 1 or fewer for women[4]), and heavy drinking (defined as 15 or more weekly drinks for men, or 8 or more for women). 

In some studies, heavy drinking has been shown to double the already-increased overall cancer risk associated with moderate drinking. For specific cancers, that increase might be even greater.

Besides the increased cancer risk, heavy drinking causes other serious health problems: 

  • Heart disease and increased risk of stroke
  • Liver disease and scarring of the liver (cirrhosis)
  • Dementia 
  • Weakened immune system
  • Miscarriage and fetal abnormalities (if consumed during pregnancy)
  • Depression
  • Bodily injury (from falls, vehicular crashes, and violence)

However, because of the dose-responsiveness of alcohol, reducing your consumption can significantly reduce your risk. Cutting back to moderate levels of drinking won’t entirely eliminate the risks posed by alcohol, but it will mitigate them significantly.

The Verdict
Sources

[1] Alcohol Use and Cancer. American Cancer Society. 2024

[2] Mutagenic, cancerogenic and teratogenic effects of alcohol. Mutation Research

[3] Cancer risk based on alcohol consumption levels: a comprehensive systematic review and meta-analysis. Epidemiology and Health. Oct 16 2023

[4] Alcohol and Cancer. Centers for Disease Control and Prevention. Jun 17 2024

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